Sadie Keesy 5/28/19 Sadie Keesy 5/28/19

Research

The Research

All of our products are blended, quality checked, packaged in glass and shipped directly from Wisconsin, USA.

Our Essential Oils and Diffusing Mediums come directly from the organic farms the plants are grown and produced, or are bought from the vendors the farms use, and are further tested for purity.

Included below you will find a list of Scientific Studies that form the foundation of our Workplace and Business formulas. There are numerus studies provided for your reading pleasure. All of our studies are non-biased, we will never pay to produce skewed results. We base everything on a true scientific process from accredited scientists or accredited educational organizations that have no motive to produce results beyond the true outcomes of the study.

PLEASE READ

Please do not underestimate the power of essential oils! Regardless of the numerous research studies, the tests for safety, and our specifically formulated blends based off of this information. We all have unique DNA! Ultimately, your body’s response to ANY form of stimuli can be different from another person, even someone that is related to you. The appreciation of the essential oil profile may not be the same for you as it for someone else. On a more serious note, if the blend contains something you are allergic to, do not use it. Just like peanuts may not be considered dangerous or toxic, to a person that has an allergy it will absolutely cause significant harm to that person. As an INFJ personality type, I strive to make a positive impact in peoples lives, and have created these formulas to benefit you. But, please be true to your own experience. Your safety is of the upmost importance! I stand behind all of my products 100%, but I Always,Always want you to speak with you physician if you have questions about use, also to test your own bodies tolerance to any new essential oils by limiting the initial exposure to determine your own body’s response to it. If you have any concerns before selecting a blend or using an essential oil please consult your physician first. The use of these products does not replace or substitute medical intervention. These products are created with safety in mind, however you should use at your own risk. Use products as directed only. Never apply concentrated products directly to skin. Always test products you have not used before to determine your sensitivity to them. Never ingest. never place inside any mucous membrane, never apply in eyes.

Nakhaee S, Kooshki A, Hormozi A, Akbari A, Mehrpour O, Farrokhfall K. Cinnamon and cognitive function: a systematic review of preclinical and clinical studies. Nutr Neurosci. 2024 Feb;27(2):132-146. doi: 10.1080/1028415X.2023.2166436. Epub 2023 Jan 18. PMID: 36652384.

Koulivand, P. H., Khaleghi Ghadiri, M., & Gorji, A. (2013). Lavender and the nervous system. Evidence-based complementary and alternative medicine : eCAM, 2013, 681304. https://doi.org/10.1155/2013/681304

Prashar, A., Locke, I. C., & Evans, C. S. (2004). Cytotoxicity of lavender oil and its major components to human skin cells. Cell proliferation, 37(3), 221–229. https://doi.org/10.1111/j.1365-2184.2004.00307.x

Mori, H. M., Kawanami, H., Kawahata, H., & Aoki, M. (2016). Wound healing potential of lavender oil by acceleration of granulation and wound contraction through induction of TGF-β in a rat model. BMC complementary and alternative medicine, 16, 144. https://doi.org/10.1186/s12906-016-1128-7

Afghan, R., Heysieattalab, S., Zangbar, H. S., Ebrahimi-Kalan, A., Jafari-Koshki, T., & Samadzadehaghdam, N. (2024). Lavender Essential Oil Inhalation Improves Attentional Shifting and Accuracy: Evidence from Dynamic Changes of Cognitive Flexibility and Power Spectral Density of Electroencephalogram Signals. Journal of medical signals and sensors, 14, 12. https://doi.org/10.4103/jmss.jmss_57_23

Can S, Yildirim Usta Y, Yildiz S, Tayfun K. The effect of lavender and rosemary aromatherapy application on cognitive functions, anxiety, and sleep quality in the elderly with diabetes. Explore (NY). 2024 Nov-Dec;20(6):103033. doi: 10.1016/j.explore.2024.103033. Epub 2024 Jul 11. PMID: 39047346.

Jiong Zhang, Min Zhang, Bhesh Bhandari & Mingqi Wang. (2024) Basic sensory properties of essential oils from aromatic plants and their applications: a critical review. Critical Reviews in Food Science and Nutrition 64:20, pages 6990-7003.

Cong Zhang, Hang Mu, Yong-Fang Yang, Yong Zhang & Wen-Jun Gou. (2023) Effect of aromatherapy on quality of life in maintenance hemodialysis patients: a systematic review and meta-analysis. Renal Failure 45:1.

Nupur Vasdev, Mayank Handa, Prashant Kesharwani & Rahul Shukla. (2022) Rosemary oil low energy nanoemulsion: optimization, µrheology, in silico, in vitro, and ex vivo characterization. Journal of Biomaterials Science, Polymer Edition 33:15, pages 1901-1923.

Francesca Saporito, Giuseppina Sandri, Maria Cristina Bonferoni, Silvia Rossi, Cinzia Boselli, Antonia Icaro Cornaglia, Barbara Mannucci, Pietro Grisoli, Barbara Vigani & Franca Ferrari. (2018) Essential oil-loaded lipid nanoparticles for wound healing. International Journal of Nanomedicine 13, pages 175-186.

O.V. Filiptsova, L.V. Gazzavi-Rogozina, I.A. Timoshyna, O.I. Naboka, Ye.V. Dyomina & A.V. Ochkur. (2018) The effect of the essential oils of lavender and rosemary on the human short-term memory. Alexandria Journal of Medicine 54:1, pages 41-44.

Maryam Rahnama, Mahmoud Mahmoudi, Shahrzad Zamani Taghizadeh Rabe, Mahdi Balali-Mood, Gholamreza Karimi, Nafiseh Tabasi & Bamdad Riahi-Zanjani. (2015) Evaluation of anti-cancer and immunomodulatory effects of carnosol in a Balb/c WEHI-164 fibrosarcoma model. Journal of Immunotoxicology 12:3, pages 231-238.

Mariem Ben Jemia, Rosa Tundis, Alessandro Pugliese, Francesco Menichini, Felice Senatore, Maurizio Bruno, Mohamed Elyes Kchouk & Monica Rosa Loizzo. (2015) Effect of bioclimatic area on the composition and bioactivity of Tunisian Rosmarinus officinalis essential oils. Natural Product Research 29:3, pages 213-222.

G. N. Martin & A. Chaudry. (2014) Working memory performance and exposure to pleasant and unpleasant ambient odor: Is spatial span special?. International Journal of Neuroscience 124:11, pages 806-811.

Yuichiro Kato, Hiroshi Endo, Tatsu Kobayakawa, Kazuhiro Kato & Satoshi Kitazaki. (2012) Effects of intermittent odours on cognitive-motor performance and brain functioning during mental fatigue. Ergonomics 55:1, pages 1-11.

Ya-ni Wu, Jian Huang, An-lian Zuo & Lei Yao. (2011) Research on the Effects of Rosemary (Rosmarinus officinalis L.) on the Blood Lipids and Anti-lipid Peroxidation in Rats. Journal of Essential Oil Research 23:4, pages 26-34.

Catherine Ulbricht, Tracee Rae Abrams, Ashley Brigham, James Ceurvels, Jessica Clubb, Whitney Curtiss, Catherine DeFranco Kirkwood, Nicole Giese, Kevin Hoehn, Ramon Iovin, Richard Isaac, Erica Rusie, Jill M. Grimes Serrano, Minney Varghese, Wendy Weissner & Regina C. Windsor. (2010) An Evidence-Based Systematic Review of Rosemary (Rosmarinus officinalis) by the Natural Standard Research Collaboration. Journal of Dietary Supplements 7:4, pages 351-413.

Benjamin Wiegand, Kathryn Luedtke, Diana Friscia, Mona Nair, Margaret Aleles & Richard McCloskey. (2010) Efficacy of a comprehensive program for reducing stress in women: A prospective, randomized trial. Current Medical Research and Opinion 26:4, pages 991-1002.

Rachel S. Herz. (2009) Aromatherapy Facts and Fictions: A Scientific Analysis of Olfactory Effects on Mood, Physiology and Behavior. International Journal of Neuroscience 119:2, pages 263-290.

Zhang, N., Chen, J., Dong, W., & Yao, L. (2022). The Effect of Copaiba Oil Odor on Anxiety Relief in Adults under Mental Workload: A Randomized Controlled Trial. Evidence-based complementary and alternative medicine : eCAM, 2022, 3874745. https://doi.org/10.1155/2022/3874745

Gomes, Niele Matos et al. “Antinoci 1. Gomes, Niele Matos et al. “Antinociceptive activity of Amazonian Copaiba oils.” Journal of ethnopharmacology vol. 109,3 (2007): 486-92. doi:10.1016/j.jep.2006.08.018

Centers for Disease Control and Prevention. (2020, September 1). Types of pneumococcal disease. Centers for Disease Control and Prevention. https://www.cdc.gov/pneumococcal/about/infection-types.html

Hebert, Patricia et al. “Treatments for Inflammatory Arthritis: Potential But Unproven Role of Topical Copaiba.” Integrative medicine (Encinitas, Calif.) vol. 16,2 (2017): 40-42.

Florida Atlantic University. (2017, June 6). Copaiba: Silver bullet or snake oil?. ScienceDaily. Retrieved March 6, 2026 from www.sciencedaily.com/releases/2017/06/170606101417.htm

Chou, S. T., Peng, H. Y., Hsu, J. C., Lin, C. C., & Shih, Y. (2013). Achillea millefolium L. essential oil inhibits LPS-induced oxidative stress and nitric oxide production in RAW 264.7 macrophages. International Journal of Molecular Sciences, 14(7), 12978-12993.

Barbosa, Maiara M C et al. “Copaiba Oil Decreases Oxidative Stress and Inflammation But not Colon Damage in Rats with TNBS-Induced Colitis.” Endocrine, metabolic & immune disorders drug targets vol. 18,3 (2018): 268-280. doi:10.2174/1871530318666180215102029

Seniya, S. P., & Jain, V. (2022). Decoding phage resistance by mpr and its role in survivability of Mycobacterium smegmatis. Nucleic acids research, 50(12), 6938–6952. https://doi.org/10.1093/nar/gkac505

Teixeira, Francisco Bruno et al. “Copaiba oil-resin (Copaifera reticulata Ducke) modulates the inflammation in a model of injury to rats’ tongues.” BMC complementary and alternative medicine vol. 17,1 313. 14 Jun. 2017, doi:10.1186/s12906-017-1820-2

Dias, Débora S et al. “Copaiba oil suppresses inflammatory cytokines in splenocytes of C57Bl/6 mice induced with experimental autoimmune encephalomyelitis (EAE).” Molecules (Basel, Switzerland) vol. 19,8 12814-26. 21 Aug. 2014, doi:10.3390/molecules190812814

Guimarães-Santos, A., Santos, D. S., Santos, I. R., Lima, R. R., Pereira, A., de Moura, L. S., Carvalho, R. N., Jr, Lameira, O., & Gomes-Leal, W. (2012). Copaiba oil-resin treatment is neuroprotective and reduces neutrophil recruitment and microglia activation after motor cortex excitotoxic injury. Evidence-based complementary and alternative medicine : eCAM, 2012, 918174. https://doi.org/10.1155/2012/918174

da Silva, Ary Gomes et al. “Application of the essential oil from copaiba (Copaifera langsdori Desf.) for acne vulgaris: a double-blind, placebo-controlled clinical trial.” Alternative medicine review : a journal of clinical therapeutic vol. 17,1 (2012): 69-75.

Gevrenova, R., Kostadinova, I., Stefanova, A., Balabanova, V., Zengin, G., Zheleva-Dimitrova, D., & Momekov, G. (2023). Phytochemical Profiling, Antioxidant and Cognitive-Enhancing Effect of Helichrysum italicum ssp. italicum (Roth) G. Don (Asteraceae). Plants (Basel, Switzerland), 12(15), 2755. https://doi.org/10.3390/plants12152755

Zhang, Nan et al. “The Effect of Copaiba Oil Odor on Anxiety Relief in Adults under Mental Workload: A Randomized Controlled Trial.” Evidence-based complementary and alternative medicine : eCAM vol. 2022 3874745. 20 Mar. 2022, doi:10.1155/2022/3874745

Vitale, S., Colanero, S., Placidi, M., Di Emidio, G., Tatone, C., Amicarelli, F., & D’Alessandro, A. M. (2022). Phytochemistry and biological activity of medicinal plants in wound healing: an overview of current research. Molecules, 27(11), 3566. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9182061/

de Mel lo, N.P., Carlos Ramos Espinoza, F., da Silva Claudiano, G. et al. Copaiba oil’s bactericidal activity and its effects on health and zootechnical performance for Nile tilapia after oral supplementation. Sci Rep 14, 17405 (2024). https://doi.org/10.1038/s41598-024-66024-x

Chou, S. T., Peng, H. Y., Hsu, J. C ., Lin, C. C., & Shih, Y. (2013). Achillea millefolium L. essential oil inhibits LPS-induced oxidative stress and nitric oxide production

Tobouti, Priscila Lie et al. “Antimicrobial activity of copaiba oil: A review and a call for further research.” Biomedicine & pharmacothe rapy = Biomedecine & pharmacotherapie vol. 94 (2017): 93-99. doi:10.1016/j.biopha.2017.07.092

Wang, C.J., Song, Y., Li, T., Hu, J., Ch en, X., & Li, H. Mycobacterium smegmati s skin infection following cosmetic procedures: Report of two cases. Clinical, Cosmetic and Investigational Journal , 15, 535-540.

MARK MOSS, STEVEN HEWITT, LUCY MOSS & KEITH WESNES. (2008) MODULATION OF COGNITIVE PERFORMANCE AN D MOOD BY AROMAS OF PEPPERMINT AND YLANG-Y LANG. International Journal of Neuroscience 118:1, pages 59-77.

Bethany Harries, Lauriane Suyin Chalmin-Pui, Birgitta Gatersleben, Alistair Griffiths & Eleanor Ratcliffe. Identifying features within a garden linked to emotional reactions and perceived restoration. Cities & Health 0:0, pages 1-13.

____

Son, J. W., Kang, P., Min, S. S., & Seol, G. H. (2025). Differential effects of clary sage (Salvia sclarea L.) oil and linalyl acetate on depression levels in diabetic foot ulcer patients with T2DM: a randomized blinded controlled trial. Frontiers in medicine, 12, 1523441. https://doi.org/10.33 89/fmed.2025.1523441

Ahmed, R., Venkatesan, K., Sivadasan, D., Sirag, N., Elfadil, H., Anbumani, G., & Saha, D. (2025). Mechanistic insights into clary sage oils role in wound heal ing: targeting oxidative stress and in flammatory pathways. Frontiers in pharmacology, 16, 1567205. https://doi.org/10.3389/fphar.2025.1567205

Kobayashi, T., Nakama, W., Yamashita, M., Kondo, K., Tsuji, S., Shioda, S., & Takenoya, F. (2026). Effects of Inhaling Cla ry Sage (Salvia sclarea L.) Essential Oil on Dysmenorrhea-Related Symptoms, Salivary Antioxidant Capacity, and Hormone Levels in Female Collegiate Athletes: A Randomized Crossover Trial. Applied Sciences, 16(7), 3234. https://doi.org/10.3390/app16073234

Moss, M., Howarth, J., & Moss, H. (2025). Aroma of Genius Essential Oil Blend Significantly Enhances Cognitive Performance and Brain Metabolism in Healthy Adults. Human psychopharmacology, 40(6), e70027. https://doi.org/10.100 2/hup.70027

Lopresti A. L. (2017). Salvia (Sage): A Review of its Potential Cognitive-Enhancing and Protective Effects. Drugs in R&D, 17(1), 53–64. https://doi.org/10.1007/s40268-016-0157-5

—

Rath, C. C., Devi, S., Dash, S. K., & Mishra, R. K. (2008). Antibacterial potential assessment of jasmine essential oil against e. Coli. Indian journal of pharmaceutical sciences, 70(2), 238–241. https://doi.org/10.410 3/0250-474X.41465

Hajabdollahi, Z., Lori poor, M., Mohseni, M., & Khalili, P. (2025). A comparison of the effect of aromatherapy with Jasmine (Jasminum) and clary sage (Salvia officinalis) on sexual dysfunction in women of reproductive age: A randomized controlled clinical trial. Journal of education and health promotion, 14, 50. https://doi.org/10.4103/jehp.jehp_1175_23

Sayowan, Winai & Siripornpanich, Vorasith & Hongratanaworakit, Tapanee & Kotchabhakdi, Naiphinich & Ruangrungsi, Nijsiri. (2013). The effects of jasmine Oil inhalation on brain wave activies and emotions. Journal of Health Research. 27. 73-77.

Hongratanaworakit T. Stimulating effect of aromatherapy massage with jasmine oil. Nat Prod Commun. 2010 Jan;5(1):157-62. PMID: 20184043.

Jafarzadeh Samani, M., Ziaei, S., Monjezi, N., Fazaeli, R., Sedaghat, N., Panahi, H., & Mortazavi, S. (2024). Anxiolytic Effect of Jasmine Aromather apy in Pediatric Dental Procedures: A Single-Blinded Randomized Placebo-Controlled Trial. Frontiers in dentistry, 21, 39. https://doi.org/10.18502/fid.v21i39.16731

—-

Sayorwan, W., Ruangrungsi, N., Piriyapunyporn, T., Hongratanaworakit, T., Kotchabha kdi, N., & Siripornpanich, V. (2013). Effects of inhaled rosemary oil on subjective feelings and activities of the nervous system. Scientia pharmaceutica, 81(2), 531–542. https://doi.org/10.3797/scipharm.1209-05

Ghasemzadeh Rahbardar, M., & Hosseinzadeh, H. (2020). Therapeutic effects of rosemary (Rosmarinus officinalis L.) and its active constituents on nervous system disorders. Iranian journal of basic medical sciences, 23(9), 1100–1112. https://doi.or g/10.22038/ijbms.2020.45269.10541

—

Stea, S., Beraudi, A., & De Pasquale, D. (2014). Essential oils for complementary treatment of surgical patients: state of the art. Evidence-based complementary and alternative medicine : eCAM, 2014, 726341. https://doi.org/10.1155/2014/726341

Choi, S. Y., Kang, P., Lee, H. S., & Seol, G. H. (2014). Effects of Inhalation of Essential Oil of Citrus aurantium L. var. amara on Menopausal Symptoms, Stress, and Estrogen in Postmenopausal Women: A Randomized Controlled Trial. Evidence-based complementary and alternative medicine : eCAM, 2014, 796518. https://doi.org/10.1155/2014/796518

Scandurra, C., Mezzalira, S., Cutillo, S., Zapparella, R., Statti, G., Maldonato, N. M., Locci, M., & Bochicchio, V. (2022). The Effectiveness of Neroli Essential Oil in Relieving Anxiety and Perceived Pain in Women during Labor: A Randomized Controlled Trial. Healthcare (Basel, Switzerland), 10(2), 366. https://doi.org/10.3390/healthcare10020366

Chen, Ying-Ju & Cheng, Fuchou & Shih, Ying & Chang, Tsong-Min & Wang, Ming-Fu & Lan, Sen-Sen. (2008). Inhalation of Neroli Essential Oil and Its Anxiolytic Effects. Journal of Complementary and Integrative Medicine. 5. 10.2202/1553-3840.1143.

—-

Bagetta G, Morrone LA, Rombolà L, Amantea D, Russo R, Berliocchi L, Sakurada S, Sakurada T, Rotiroti D, Corasaniti MT. Neuropharmacology of the essential oil of bergamot. Fitoterapia. 2010 Sep;81(6):453-61. doi: 10.1016/j.fitote.2010.01.013. Epub 2010 Jan 20. PMID: 20093169.

Daniel, D. R., & Zolnikov, T. R. (2023). The Use of Bergamot Essential Oil for PTSD Symptomology: A Qualitative Study. American Journal of Qualitative Research, 7(4), 1-32. https://doi.org/10.29333/ajqr/13596

Fogacci, F., Giovannini, M., Imbalzano, E., Grandi, E., Rizzoli, E., D'Addato, S. & Cicero, A. F. (2023). Metabolic and vascular effect of a new standardized bergamot phytocomplex: a three-arm, placebo controlled, double-blind clinical trial. Archives of Medical Science, 19(5), 1228–1235. https://doi.org/10.5114/aoms/163368

Perna, S., Spadaccini, D., Botteri, L., Girometta, C., Riva, A., Allegrini, P., Petrangolini, G., Infantino, V., & Rondanelli, M. (2019). Efficacy of bergamot: From anti-inflammatory and anti-oxidative mechanisms to clinical applications as preventive agent for cardiovascular morbidity, skin diseases, and mood alterations. Food science & nutrition, 7(2), 369–384. https://doi.org/10.1002/fsn3.903

Adorisio, S., Muscari, I., Fierabracci, A., Thi Thuy, T., Marchetti, M. C., Ayroldi, E., & Delfino, D. V. (2023). Biological effects of bergamot and its potential therapeutic use as an anti-inflammatory, antioxidant, and anticancer agent. Pharmaceutical biology, 61(1), 639–646. https://doi.org/10.1080/13880209.2023.2197010

—

Carson, C. F., Hammer, K. A., & Riley, T. V. (2006). Melaleuca alternifolia (Tea Tree) oil: a review of antimicrobial and other medicinal properties. Clinical microbiology reviews, 19(1), 50–62. https://doi.org/10.1128/CMR.19.1.50-62.2006

Kairey, L., Agnew, T., Bowles, E. J., Barkla, B. J., Wardle, J., & Lauche, R. (2023). Efficacy and safety of Melaleuca alternifolia (tea tree) oil for human health-A systematic review of randomized controlled trials. Frontiers in pharmacology, 14, 1116077. https://doi.org/10.3389/fphar.2023.1116077

Halcón L, Milkus K, Staphylococcus aureus and wounds: A review of tea tree oil as a promising antimicrobial American Journal of Infection Control, 32, 402-408

——

Tan, L. T., Lee, L. H., Yin, W. F., Chan, C. K., Abdul Kadir, H., Chan, K. G., & Goh, B. H. (2015). Traditional Uses, Phytochemistry, and Bioactivities of Cananga odorata (Ylang-Ylang). Evidence-based complementary and alternative medicine : eCAM, 2015, 896314. https://doi.org/10.1155/2015/896314

Jung, D. J., Cha, J. Y., Kim, S. E., Ko, I. G., & Jee, Y. S. (2013). Effects of Ylang-Ylang aroma on blood pressure and heart rate in healthy men. Journal of exercise rehabilitation, 9(2), 250–255. https://doi.org/10.12965/jer.130007

Hongratanaworakit T, Buchbauer G. Relaxing effect of ylang ylang oil on humans after transdermal absorption. Phytother Res. 2006 Sep;20(9):758-63. doi: 10.1002/ptr.1950. PMID: 16807875.

—-

Cheaha, D., Issuriya, A., Manor, R., Kwangjai, J., Rujiralai, T., & Kumarnsit, E. (2016). Modification of sleep-waking and electroencephalogram induced by vetiver essential oil inhalation. Journal of intercultural ethnopharmacology, 5(1), 72–78. https://doi.org/10.5455/jice.20160208050736

Anindita Gogoi, Roktim Gogoi, Twahira Begum, Neelav Sarma, Mohan Lal, Kahkashan Perveen, Najla A. Alshaikh & Jamilah A. Alsulami. (2023) Chemical constituent and Biological potency of Chrysopogon zizanoides L. root essential oil grown in North-East India with special consideration to acidic soil. Journal of Essential Oil Bearing Plants 26:4, pages 920-936.

Xuesheng Han & Tory L. Parker. (2017) Cardamom (Elettaria cardamomum) essential oil significantly inhibits vascular cell adhesion molecule 1 and impacts genome-wide gene expression in human dermal fibroblasts. Cogent Medicine 4:1.

Xuesheng Han & Tory L. Parker. (2017) Anti-inflammatory activity of clove (Eugenia caryophyllata) essential oil in human dermal fibroblasts. Pharmaceutical Biology 55:1, pages 1619-1622.

Burger, P., Landreau, A., Watson, M., Janci, L., Cassisa, V., Kempf, M., Azoulay, S., & Fernandez, X. (2017). Vetiver Essential Oil in Cosmetics: What Is New?. Medicines (Basel, Switzerland), 4(2), 41. https://doi.org/10.3390/medicines4020041

Gunasekar, C. J., Majdalawieh, A. F., Abu-Yousef, I. A., & Al Refaai, S. A. (2025). Pharmacological and Therapeutic Potential of Chrysopogon zizanioides (Vetiver): A Comprehensive Review of Its Medicinal Applications and Future Prospects. Biomolecules, 15(9), 1312. https://doi.org/10.3390/biom15091312

Cheaha, Dania & Issuriya, Acharaporn & Manor, Rodiya & Kwangjai, Jackapun & Rujiralai, Thitima & Kumarnsit, Ekkasit. (2016). Modification of sleep-waking and electroencephalogram induced by vetiver essential oil inhalation. Journal of Intercultural Ethnopharmacology. 5. 72. 10.5455/jice.20160208050736.

—-

Ok E, Kocatepe V, Ünver V. The effect of the rose essential oil aroma on university students’ learning and short-term memory: A randomized controlled trial. J CLIN MED KAZ. 2021;18(1):32-7. https://doi.org/10.23950/jcmk/9651

Hongratanaworakit T. Relaxing effect of rose oil on humans. Nat Prod Commun. 2009 Feb;4(2):291-6. PMID: 19370942.

Antonova, D. V., Medarska, Y. N., Stoyanova, A. S., Nenov, N. S., Slavov, A. M., & Antonov, L. M. (2020). Chemical profile and sensory evaluation of Bulgarian rose (Rosa damascena Mill.) aroma products, isolated by different techniques. Journal of Essential Oil Research. https://doi.org/10.1080/10412905.2020.1839583

Başer, K. H. C. (2017). Rose mentioned in the works of scientists of the Medieval East and implications in modern science. Acta Horticulturae, 1152, 177–182. https://doi.org/10.17660/ActaHortic.2017.1152.26

de Sousa, D. P., de Almeida Soares Hocayen, P., Andrade, L. N., & Andreatini, R. (2015). A Systematic Review of the Anxiolytic-Like Effects of Essential Oils in Animal Models. Molecules (Basel, Switzerland), 20(10), 18620–18660. https://doi.org/10.3390/molecules201018620

Gale, M. (2025, August 27). Understanding IFRA standards. Marie Gale. https://www.mariegale.com/understanding-ifra-standards/

Happy, A. A., Jahan, F., & Momen, M. A. (2021). Essential oils: Magical ingredients for skin care. Journal of Plant Sciences, 9(2), 54–64. https://doi.org/10.11648/j.jps.20210902.14

“Jayaraj, R. L., Azimullah, S., Parekh, K. A., Ojha, S. K., & Beiram, R. (2022). Effect of citronellol on oxidative stress, neuroinflammation and autophagy pathways in an in vivo model of Parkinson’s disease. Heliyon, 8(11), Article e11434. https://doi.org/10.1016/j.heliyon.2022.e11434

Lin, L., Long, N., Qiu, M., Liu, Y., Sun, F., & Dai, M. (2021). The inhibitory efficiencies of geraniol as an anti-inflammatory, antioxidant, and antibacterial natural agent against methicillin-resistant Staphylococcus aureus infection in vivo. Infection and Drug Resistance, 14, 2991–3000. https://doi.org/10.2147/IDR.S318989

Mączka, W., Wińska, K., & Grabarczyk, M. (2020). One hundred faces of geraniol. Molecules, 25(14), 3303. https://doi.org/10.3390/molecules25143303

Mohammadi Nejad, S., Özgüneş, H., & Başaran, N. (2017). Pharmacological and toxicological properties of eugenol. Turkish Journal of Pharmaceutical Sciences, 14(2), 201–206. https://doi.org/10.4274/tjps.62207

Niazi, M., Hashempur, M. H., Taghizadeh, M., Heydari, M., & Shariat, A. (2017). Efficacy of topical Rose (Rosa damascena Mill.) oil for migraine headache: A randomized double-blinded placebo-controlled cross-over trial. Complementary therapies in medicine, 34, 35–41. https://doi.org/10.1016/j.ctim.2017.07.009

Nasiri, M., Torkaman, M., Feizi, S., Bigdeli Shamloo, M. B., & others. (2021). Effect of aromatherapy with Damask rose on alleviating adults’ acute pain severity: A systematic review and meta-analysis of randomized controlled trials. Complementary Therapies in Medicine, 56, Article 102596. https://doi.org/10.1016/j.ctim.2020.102596

Petersen, D. (2014). Essential Oil of Rose Monograph [Course material]. American College of Healthcare Sciences.

Petersen, D. (2016). 3 reasons to love rose in your DIY skin care. American College of Healthcare Sciences Blog.

Yulianti, Y., & Awaludin, S. (2024). Inhalation of rose aromatherapy against anxiety of heart patients. Eduvest – Journal of Universal Studies, 4(3), 1310–1321. https://eduvest.greenvest.co.id/index.php/edv/article/view/1053/1991

Mohebitabar, S., Shirazi, M., Bioos, S., Rahimi, R., Malekshahi, F., & Nejatbakhsh, F. (2017). Therapeutic efficacy of rose oil: A comprehensive review of clinical evidence. Avicenna journal of phytomedicine, 7(3), 206–213.

—-

Sriraksa, N., Kongsui, R., & Thongrong, S. (2022). Lotus essential oil improves neurite elongation and facilitates functional recovery after peripheral nerve injury. Biomedical reports, 16(4), 30. https://doi.org/10.3892/br.2022.1513

Jeon S, Kim NH, Koo BS, Kim JY, Lee AY. Lotus (Nelumbo nuficera) flower essential oil increased melanogenesis in normal human melanocytes. Exp Mol Med. 2009 Jul 31;41(7):517-25. doi: 10.3858/emm.2009.41.7.057. PMID: 19322028; PMCID: PMC2721149.

Jeon, S., Kim, N. H., Koo, B. S., Kim, J. Y., & Lee, A. Y. (2009). Lotus (Nelumbo nuficera) flower essential oil increased melanogenesis in normal human melanocytes. Experimental & molecular medicine, 41(7), 517–525. https://doi.org/10.3858/emm.2009.41.7.057

Kim, Nan-Hyung & Koo, Byung-Soo & Kim, Ji-Young & Lee, Ai-Young. (2009). Lotus (Nelumbo nuficera) flower essential oil increased melanogenesis in normal human melanocytes. Experimental & molecular medicine. 41. 517-25. 10.3858/emm.2009.41.7.057.

Ando H / 1995 / Correlation between the number of melanosomes, tyrosinase mRNA levels, and tyrosinase activity in cultured murine melanoma cells in response to various melanogenesis regulatory agents / J Cell Physiol / 163 : 608

—-

Shiekh, R. A. E., Atwa, A. M., Elgindy, A. M., Mustafa, A. M., Senna, M. M., Alkabbani, M. A., & Ibrahim, K. M. (2025). Therapeutic applications of eucalyptus essential oils. Inflammopharmacology, 33(1), 163–182. https://doi.org/10.1007/s10787-024-01588-8

Salvatori, E. S., Morgan, L. V., Ferrarini, S., Zilli, G. A. L., Rosina, A., Almeida, M. O. P., Hackbart, H. C. S., Rezende, R. S., Albeny-Simões, D., Oliveira, J. V., Gasparetto, A., Müller, L. G., & Dal Magro, J. (2023). Anti-Inflammatory and Antimicrobial Effects of Eucalyptus spp. Essential Oils: A Potential Valuable Use for an Industry Byproduct. Evidence-based complementary and alternative medicine : eCAM, 2023, 2582698. https://doi.org/10.1155/2023/2582698

Mahboubi M, Mokari Z. The Efficacy of <i>Eucalyptus globulus</i> Essential Oil in the Management of Pain. International Journal of Pain 2024;15:70-79. https://doi.org/10.56718/ijp.24-019

Fayez S, Gamal El-Din MI, Moghannem SA, Azam F, El-Shazly M, Korinek M, Chen Y-L, Hwang T-L and Fahmy NM (2023) Eucalyptus-derived essential oils alleviate microbes and modulate inflammation by suppressing superoxide and elastase release. Front. Pharmacol. 14:1218315. doi: 10.3389/fphar.2023.1218315

Shiekh RAE, Atwa AM, Elgindy AM, Mustafa AM, Senna MM, Alkabbani MA, Ibrahim KM. Therapeutic applications of eucalyptus essential oils. Inflammopharmacology. 2025 Jan;33(1):163-182. doi: 10.1007/s10787-024-01588-8. Epub 2024 Nov 5. PMID: 39499358; PMCID: PMC11799053.

Galan,Derick M. and Ezeudu,Ngozi E. and Garcia,Jasmine and Geronimo,Chalice A. and Berry,Nicholas M. and Malcolm,Benjamin J., 20203182545, English, Journal article, UK, doi:10.1080/10412905.2020.1716867, 2163-8152 1041-2905, 32, (2), Abingdon, Journal of Essential Oil Research, (103–110), Taylor & Francis, Eucalyptol (1,8-cineole): an underutilized ally in respiratory disorders?, (2020)

——

Kowalczyk, A., Przychodna, M., Sopata, S., Bodalska, A., & Fecka, I. (2020). Thymol and Thyme Essential Oil-New Insights into Selected Therapeutic Applications. Molecules (Basel, Switzerland), 25(18), 4125. https://doi.org/10.3390/molecules25184125

Vassiliou, E., Awoleye, O., Davis, A., & Mishra, S. (2023). Anti-Inflammatory and Antimicrobial Properties of Thyme Oil and Its Main Constituents. International journal of molecular sciences, 24(8), 6936. https://doi.org/10.3390/ijms24086936

Eqbal M. A. Dauqan1, Aminah Abdullah., Journal of Applied Biology & Biotechnology Vol. 5 (02), pp. 017-022, March-April, 2017 Available online at http://www.jabonline.in DOI: 10.7324/JABB.2017.50203

Singletary, K. Thyme: History, Applications, and Overview of Potential Health Benefits. Nutrition Today. 2016 Jan/Feb: 51(1): 40-49.

Jalil B, Pischel I, Feistel B, Suarez C, Blainski A, Spreemann R, Roth-Ehrang R and Heinrich M (2024) Wild thyme (Thymus serpyllum L.): a review of the current evidence of nutritional and preventive health benefits*. Front. Nutr. 11:1380962. doi: 10.3389/fnut.2024.1380962

Warman, D. J., Jia, H., & Kato, H. (2023). Effects of Thyme (Thymus vulgaris L.) Essential Oil on Aging-Induced Brain Inflammation and Blood Telomere Attrition in Chronologically Aged C57BL/6J Mice. Antioxidants (Basel, Switzerland), 12(6), 1178. https://doi.org/10.3390/antiox12061178

Waheed, M., Hussain, M.B., Saeed, F., Afzaal, M., Ahmed, A., Irfan, R., Akram, N., Ahmed, F. and Hailu, G.G. (2024), Phytochemical Profiling and Therapeutic Potential of Thyme (Thymus spp.): A Medicinal Herb. Food Sci Nutr, 12: 9893-9912. https://doi.org/10.1002/fsn3.4563

—-

Frazão, D. R., Cruz, J. N., Santana de Oliveira, M., Baia-da-Silva, D. C., Nazário, R. M. F., Rodrigues, M. F. L., Saito, M. T., Souza-Rodrigues, R. D., & Lima, R. R. (2023). Evaluation of the biological activities of Copaiba (Copaifera spp): a comprehensive review based on scientometric analysis. Frontiers in pharmacology, 14, 1215437. https://doi.org/10.3389/fphar.2023.1215437

Guimarães-Santos, A., Santos, D. S., Santos, I. R., Lima, R. R., Pereira, A., de Moura, L. S., Carvalho, R. N., Jr, Lameira, O., & Gomes-Leal, W. (2012). Copaiba oil-resin treatment is neuroprotective and reduces neutrophil recruitment and microglia activation after motor cortex excitotoxic injury. Evidence-based complementary and alternative medicine : eCAM, 2012, 918174. https://doi.org/10.1155/2012/918174

Cardinelli, C. C., Silva, J. E. A. e., Ribeiro, R., Veiga-Junior, V. F., Santos, E. P. d., & de Freitas, Z. M. F. (2023). Toxicological Effects of Copaiba Oil (Copaifera spp.) and Its Active Components. Plants, 12(5), 1054. https://doi.org/10.3390/plants12051054

—

Song, X., Liu, T., Wang, L., Liu, L., Li, X., & Wu, X. (2020). Antibacterial Effects and Mechanism of Mandarin (Citrus reticulata L.) Essential Oil against Staphylococcus aureus. Molecules (Basel, Switzerland), 25(21), 4956. https://doi.org/10.3390/molecules25214956

Devite, F. T., Azevedo, F. A. d., Bastianel, M., Schinor, E. H., & Conceição, P. M. d. (2023). Mandarin Essential Oils as an Alternative Method of Controlling the Fungus Alternaria alternata (Fr.: Fr.) Keissler. Horticulturae, 9(6), 613. https://doi.org/10.3390/horticulturae9060613

Sattayakhom, A., Wichit, S., & Koomhin, P. (2023). The Effects of Essential Oils on the Nervous System: A Scoping Review. Molecules (Basel, Switzerland), 28(9), 3771. https://doi.org/10.3390/molecules28093771

Song X, Liu T, Wang L, Liu L, Li X, Wu X. Antibacterial Effects and Mechanism of Mandarin (Citrus reticulata L.) Essential Oil against Staphylococcus aureus. Molecules. 2020 Oct 26;25(21):4956. doi: 10.3390/molecules25214956. PMID: 33114746; PMCID: PMC7663016.

—-

Xu, F., Shi, Y., Li, B., Liu, C., Zhang, Y., & Zhong, J. (2024). Characterization, Stability and Antioxidant Activity of Vanilla Nano-Emulsion and Its Complex Essential Oil. Foods (Basel, Switzerland), 13(5), 801. https://doi.org/10.3390/foods13050801

Tan, B. L., & Chan, L. C. (2026). How Effective Is Vanilla planifolia Beyond Flavor in Protecting Against Oxidative Stress? Romanian Journal of Preventive Medicine, 4(2), 3. https://doi.org/10.3390/rjpm4020003

Arya, S. S., Rookes, J. E., Cahill, D. M., & Lenka, S. K. (2021). Vanillin: a review on the therapeutic prospects of a popular flavouring molecule. Advances in Traditional Medicine, 21(3), 1–17. https://doi.org/10.1007/s13596-020-00531-w

Singletary, Keith. (2020). Vanilla: Potential Health Benefits. Nutrition Today. Publish Ahead of Print. 10.1097/NT.0000000000000412.

——-

Haryalchi, K., Kazemi Aski, S., Mansour Ghanaie, M., Fotouhi, M., Mansoori, R., Sadraei, S. M., Yaghobi, Y., & Olangian-Tehrani, S. (2023). Effects of the aroma of lemone verbena (Aloysia citriodora Paláu) essential oil on anxiety and the hemodynamic profile before cesarean section: A randomized clinical trial. Health science reports, 6(5), e1282. https://doi.org/10.1002/hsr2.1282

Rashid, H. M., Mahmod, A. I., Afifi, F. U., & Talib, W. H. (2022). Antioxidant and Antiproliferation Activities of Lemon Verbena (Aloysia citrodora): An In Vitro and In Vivo Study. Plants (Basel, Switzerland), 11(6), 785. https://doi.org/10.3390/plants11060785

Yousef Salama, Nidal Jaradat, Koichi Hattori, Beate Heissig. Aloysia Citrodora Essential Oil Inhibits Melanoma Cell Growth and Migration by Targeting HB-EGF-EGFR Signaling. International Journal of Molecular Sciences, 22(15), 8151, July 2021. https://doi.org/10.3390/ijms22158151

Gao, X., Liu, J., Li, B., & Xie, J. (2023). Antibacterial Activity and Antibacterial Mechanism of Lemon Verbena Essential Oil. Molecules, 28(7), 3102. https://doi.org/10.3390/molecules28073102

Haryalchi K, Kazemi Aski S, Mansour Ghanaie M, et al. Effects of the aroma of lemone verbena (Aloysia citriodora Paláu) essential oil on anxiety and the hemodynamic profile before cesarean section: a randomized clinical trial. Health Sci Rep. 2023;6:e1282. doi:10.1002/hsr2.1282

——

Sharma R, Rao R, Kumar S, Mahant S, Khatkar S. Therapeutic Potential of Citronella Essential Oil: A Review. Curr Drug Discov Technol. 2019;16(4):330-339. doi: 10.2174/1570163815666180718095041. PMID: 30019646.

Rolim, P. A. d. S., Catanoze, I. A., Fracasso, J. A. R., Barbosa, D. B., dos Santos, L., Ximenes, V. F., & Guiotti, A. M. (2024). Antifungal, Antioxidant, and Irritative Potential of Citronella Oil (Cymbopogon nardus) Associated with Phenethyl Ester of Caffeic Acid (CAPE). Cosmetics, 11(5), 162. https://doi.org/10.3390/cosmetics11050162

—

Dosoky, N. S., Poudel, A., & Satyal, P. (2022). Authentication and Market Survey of Sweet Birch (Betula lenta L.) Essential Oil. Plants (Basel, Switzerland), 11(16), 2132. https://doi.org/10.3390/plants11162132

—

Kačániová, M., Galovičová, L., Valková, V., Ďuranová, H., Štefániková, J., Čmiková, N., Vukic, M., Vukovic, N. L., & Kowalczewski, P. Ł. (2022). Chemical Composition, Antioxidant, In Vitro and In Situ Antimicrobial, Antibiofilm, and Anti-Insect Activity of Cedar atlantica Essential Oil. Plants (Basel, Switzerland), 11(3), 358. https://doi.org/10.3390/plants11030358

National Toxicology Program. NTP Technical Report on the Toxicity Studies of Cedarwood Oil (Virginia) (CASRN 8000-27-9) Administered Dermally to F344/N Rats and B6C3F1/N Mice: Toxicity Report 86 [Internet]. Research Triangle Park (NC): National Toxicology Program; 2016 Nov. Discussion. Available from: https://www.ncbi.nlm.nih.gov/books/NBK552532/

Tamer, T. M., Sabet, M. M., Alhalili, Z. A. H., Ismail, A. M., Mohy-Eldin, M. S., & Hassan, M. A. (2022). Influence of Cedar Essential Oil on Physical and Biological Properties of Hemostatic, Antibacterial, and Antioxidant Polyvinyl Alcohol/Cedar Oil/Kaolin Composite Hydrogels. Pharmaceutics, 14(12), 2649. https://doi.org/10.3390/pharmaceutics14122649

Huang K, Liu R, Zhang Y, Guan X. Characteristics of two cedarwood essential oil emulsions and their antioxidant and antibacterial activities. Food Chem. 2021 Jun 1;346:128970. doi: 10.1016/j.foodchem.2020.128970. Epub 2021 Jan 1. PMID: 33422919.

Manjula Ramadass, Padma Thiagarajan. Importance and Applications of Cedar oil. Research J. Pharm. and Tech. 8(12): Dec., 2015; Page 1714-1718. doi: 10.5958/0974-360X.2015.00308.X

—

Farasati Far, B., Behzad, G., & Khalili, H. (2023). Achillea millefolium: Mechanism of action, pharmacokinetic, clinical drug-drug interactions and tolerability. Heliyon, 9(12), e22841. https://doi.org/10.1016/j.heliyon.2023.e22841

Vanja Tadić, Ivana Arsić, Jelena Zvezdanović, Ana Zugić, Dragan Cvetković, Sava Pavkov,The estimation of the traditionally used yarrow (Achillea millefolium L. Asteraceae) oil extracts with anti-inflamatory potential in topical application, Journal of Ethnopharmacology, Volume 199, 2017,Pages 138-148, ISSN 0378-8741, https://doi.org/10.1016/j.jep.2017.02.002.

Chou, S. T., Peng, H. Y., Hsu, J. C., Lin, C. C., & Shih, Y. (2013). Achillea millefolium L. essential oil inhibits LPS-induced oxidative stress and nitric oxide production in RAW 264.7 Macrophages. International journal of molecular sciences, 14(7), 12978–12993. https://doi.org/10.3390/ijms140712978

—-

Furlan, V., & Bren, U. (2023). Helichrysum italicum: From Extraction, Distillation, and Encapsulation Techniques to Beneficial Health Effects. Foods (Basel, Switzerland), 12(4), 802. https://doi.org/10.3390/foods12040802

Kramberger, K., Kenig, S., Jenko Pražnikar, Z., Kočevar Glavač, N., & Barlič-Maganja, D. (2021). A Review and Evaluation of the Data Supporting Internal Use of Helichrysum italicum. Plants (Basel, Switzerland), 10(8), 1738. https://doi.org/10.3390/plants10081738

Serra, D., Cruciani, S., Garroni, G., Sarais, G., Kavak, F. F., Satta, R., Montesu, M. A., Floris, M., Ventura, C., & Maioli, M. (2024). Effect of Helichrysum italicum in Promoting Collagen Deposition and Skin Regeneration in a New Dynamic Model of Skin Wound Healing. International Journal of Molecular Sciences, 25(9), 4736. https://doi.org/10.3390/ijms25094736

Soltanbeigi, E., Isitez, N., Erdogmus, S. F., & Ozliman, S. (2025). Helichrysum italicum (Roth) G. Don essential oil: composition and potential anti-tumour, anti-inflammatory, antimicrobial, and antibiofilm effects. Journal of Biologically Active Products from Nature, 15(4), 353–368. https://doi.org/10.1080/22311866.2025.2533167

An, S., An, J., Lee, D., Kang, H.N., Kang, S., Ahn, C.-H., Syahputra, R.A., Ribeiro, R.I.M.A., Kim, B. (2025). Natural Products for Melanoma Therapy: From Traditional Medicine to Modern Drug Discovery. Plants. 14(6): 951. doi: 10.3390/plants14060951

Chen, L., Ju, X., Wu, X., Zuo, Z. (2024). Anti-melanoma cancer activity and chemical profile of the essential oil of Seseli yunnanense Franch. Open Chemistry. 22: 20240080. doi: 10.1515/chem-2024-0080

Staver, M.M., Gobin, I., Ratkaj, I., Petrovic, M., Vulinovic, A., Dinarina-Sablic, M., Broznic, D. (2018). In vitro Antiproliferative and Antimicrobial Activity of the Essential Oil from the Flowers and Leaves of Helichrysum italicum (Roth) G. Don Growing in Central Dalmatia (Croatia). Journal of Essential Oil Bearing Plants. 21(1): 77-91. doi: 10.1080/0972060X.2018.1433071

Ninčević, T., Grdiša, M., Šatović, Z., Jug-Dujaković, M. (2019). Helichrysum italicum (Roth) G. Don: Taxonomy, biological activity, biochemical and genetic diversity. Industrial Crops and Products. 138: 111487. doi: 10.1016/j.indcrop.2019.111487

Antunes Viegas, D., Palmeira-de-Oliveira, A., Salgueiro, L., Martinez-de-Oliveira, J., Palmeira-de-Oliveira, R. (2014). Helichrysum italicum: From traditional use to scientific data. Journal of Ethnopharmacology. 151(1): 54-65. doi: 10.1016/j.jep.2013.11.005

Genčić, M.S., Aksić, J.M., Živković Stošić, M.Z., Randjelović, P.J., Stojanović, N.M., Stojanović-Radić, Z.Z., Radulović, N.S. (2021). Linking the antimicrobial and anti-inflammatory effects of immortelle essential oil with its chemical composition – The interplay between the major and minor constituents. Food and Chemical Toxicology. 158: 112666. doi: 10.1016/j.fct.2021.112666

Djihane, B., Wafa, N., Elkhamssa, S., Pedro, H.J., Maria, A.E., Mohamed Mihoub, Z. (2017). Chemical constituents of Helichrysum italicum (Roth) G. Don essential oil and their antimicrobial activity against Gram-positive and Gram-negative bacteria, filamentous fungi and Candida albicans. Saudi Pharm. J. 25(5): 780-787. doi: 10.1016/j.jsps.2016.11.001

Fraternale, D., Flamini, G., Ascrizzi, R. (2019). In Vitro Anticollagenase and Antielastase Activities of Essential Oil of Helichrysum italicum subsp. italicum (Roth) G. Don. J. Med. Food. 22(10): 1041-1046. doi: 10.1089/jmf.2019.0054

Erdoğmuş, S.F., Bilecen, C., Erdal Altıntaş, Ö., Ulukütük, S., Kargıoğlu, M. (2022). The antibiofilm effects of some Cistus spp. against pathogenic microorganisms. International Journal of Plant Based Pharmaceuticals. 2(2): 252-260. doi: 10.29228/ijpbp.7

Sala, A., Recio, M., Giner, R.M., Máñez, S., Tournier, H., Schinella, G., Ríos, J.L. (2002). Anti-inflammatory and antioxidant properties of Helichrysum italicum. J. Pharm. Pharmacol. 54(3): 365-71. doi: 10.1211/0022357021778600

Jakupović, L., Bačić, I., Jablan, J., Marguí, E., Marijan, M., Inić, S., Nižić Nodilo, L., Hafner, A., Zovko Končić, M. (2023). Hydroxypropyl-β-Cyclodextrin-Based Helichrysum italicum Extracts: Antioxidant and Cosmeceutical Activity and Biocompatibility. Antioxidants (Basel). 12(4): 855. doi: 10.3390/antiox12040855

Tira, S., Modica, G.D. (1967). New β-diketones from Helichrysum italicum g. don. Tetrahedron Letters. 8(2): 143-148. doi: 10.1016/S0040-4039(00)90504-5

Kramberger, K., Jenko Pražnikar, Z., Baruca Arbeiter, A., Petelin, A., Bandelj, D., Kenig, S. (2021). A Comparative Study of the Antioxidative Effects of Helichrysum italicum and Helichrysum arenarium Infusions. Antioxidants (Basel). 10(3): 380. doi: 10.3390/antiox10030380

Anand P, Sundaram C, Jhurani S, Kunnumakkara AB, Aggarwal BB. Curcumin and cancer: an "old-age" disease with an "age-old" solution. Cancer Lett. 2008 Aug 18;267(1):133-64. doi: 10.1016/j.canlet.2008.03.025. Epub 2008 May 6. PMID: 18462866.

Nazzaro F, Fratianni F, De Martino L, Coppola R, De Feo V. Effect of essential oils on pathogenic bacteria. Pharmaceuticals (Basel). 2013 Nov 25;6(12):1451-74. doi: 10.3390/ph6121451. PMID: 24287491; PMCID: PMC3873673.

——

Alahmady, N. F., Alkhulaifi, F. M., Abdullah Momenah, M., Ali Alharbi, A., Allohibi, A., Alsubhi, N. H., & Ahmed Alhazmi, W. (2024). Biochemical characterization of chamomile essential oil: Antioxidant, antibacterial, anticancer and neuroprotective activity and potential treatment for Alzheimer's disease. Saudi journal of biological sciences, 31(2), 103912. https://doi.org/10.1016/j.sjbs.2023.103912

Sah, A., Naseef, P. P., Kuruniyan, M. S., Jain, G. K., Zakir, F., & Aggarwal, G. (2022). A Comprehensive Study of Therapeutic Applications of Chamomile. Pharmaceuticals (Basel, Switzerland), 15(10), 1284. https://doi.org/10.3390/ph15101284

Batovska, D., Panova, N., Gerasimova, A., Tumbarski, Y., Ivanov, I., Dincheva, I., Yotkovska, I., Gentscheva, G., & Nikolova, K. (2025). Chamomile Matters: Species- and Producer-Dependent Variation in Bulgarian Matricaria recutita L. and Chamaemelum nobile L. Essential Oils and Their Cosmetic Potential. Cosmetics, 12(3), 123. https://doi.org/10.3390/cosmetics12030123

Frydrysiak, E., Śmigielski, K., Kunicka-Styczyńska, A., & Frydrysiak, M. (2024). Investigation of Releasing Chamomile Essential Oil from Inserts with Cellulose Agar and Microcrystalline Cellulose Agar Films Used in Biotextronics Systems for Lower Urinary Tract Inflammation Treatment. Materials (Basel, Switzerland), 17(16), 4119. https://doi.org/10.3390/ma17164119

——-

Chandharakool, S., Koomhin, P., Sinlapasorn, J., Suanjan, S., Phungsai, J., Suttipromma, N., Songsamoe, S., Matan, N., & Sattayakhom, A. (2020). Effects of Tangerine Essential Oil on Brain Waves, Moods, and Sleep Onset Latency. Molecules (Basel, Switzerland), 25(20), 4865. https://doi.org/10.3390/molecules25204865

Shi, M., Guo, Q., Xiao, Z., Sarengaowa, Xiao, Y., & Feng, K. (2024). Recent Advances in the Health Benefits and Application of Tangerine Peel (Citri Reticulatae Pericarpium): A Review. Foods (Basel, Switzerland), 13(13), 1978. https://doi.org/10.3390/foods13131978

——-

Moayedi, Y., Greenberg, S. A., Jenkins, B. A., Marshall, K. L., Dimitrov, L. V., Nelson, A. M., Owens, D. M., & Lumpkin, E. A. (2019). Camphor white oil induces tumor regression through cytotoxic T cell-dependent mechanisms. Molecular carcinogenesis, 58(5), 722–734. https://doi.org/10.1002/mc.22965

Shabbir, A., & Parvinzadeh Gashti, M. (2026). Camphor's Therapeutic Uses and Potential Hazards: An In-Depth Review of Its Medicinal Applications. Molecules (Basel, Switzerland), 31(4), 648. https://doi.org/10.3390/molecules31040648

—-

Kusuma, I. Y., Perdana, M. I., Vágvölgyi, C., Csupor, D., & Takó, M. (2024). Exploring the Clinical Applications of Lemongrass Essential Oil: A Scoping Review. Pharmaceuticals (Basel, Switzerland), 17(2), 159. https://doi.org/10.3390/ph17020159

Mukarram, M., Choudhary, S., Khan, M. A., Poltronieri, P., Khan, M. M. A., Ali, J., Kurjak, D., & Shahid, M. (2021). Lemongrass Essential Oil Components with Antimicrobial and Anticancer Activities. Antioxidants (Basel, Switzerland), 11(1), 20. https://doi.org/10.3390/antiox11010020

Siqi Wan, Bingcong Xing, Research progress on chemical composition, biological activity and application of lemongrass and its essential oils, Journal of Functional Foods, Volume 135, 2025,107083, ISSN 1756-4646, https://doi.org/10.1016/j.jff.2025.107083.

Gao S, Liu G, Li J, Chen J, Li L, Li Z, Zhang X, Zhang S, Thorne RF and Zhang S (2020) Antimicrobial Activity of Lemongrass Essential Oil (Cymbopogon flexuosus) and Its Active Component Citral Against Dual-Species Biofilms of Staphylococcus aureus and Candida Species. Front. Cell. Infect. Microbiol. 10:603858. doi: 10.3389/fcimb.2020.603858

—-

Cheng, K. K., Nadri, M. H., Othman, N. Z., Rashid, S. N. A. A., Lim, Y. C., & Leong, H. Y. (2022). Phytochemistry, Bioactivities and Traditional Uses of Michelia × alba. Molecules (Basel, Switzerland), 27(11), 3450. https://doi.org/10.3390/molecules27113450

Uma Rajeswari Batchu, Kiranmai Mandava , P. N. V. Bhargav, Kiran Kumari Maddi, Mustafa Syed, Sai Prasanna Rasamalla, Sravanthi Madhira, Journal of Applied Pharmaceutical Science Vol. 7 (03), pp. 113-116, March, 2017 Available online at http://www.japsonline.com DOI: 10.7324/JAPS.2017.70318

Guo X (2026) Analysis of volatile compounds emitted from white champaca flowers (Michelia alba D.C.) via HS-GC-MS and SPME-GC-MS technology. Front. Plant Sci. 17:1780030. doi: 10.3389/fpls.2026.1780030

Ramadhan, Ahmad & Antony, Mk & Pradana, Sendy & Dewiyeti, Susi. (2025). Michelia alba: A Review on Its Biological Profile and Ethnobotany in Java. Jurnal Indonesia Sosial Teknologi. 6. 69-89. 10.59141/jist.v6i1.8886.

—-

Kamelnia, E., Mohebbati, R., Kamelnia, R., El-Seedi, H. R., & Boskabady, M. H. (2023). Anti-inflammatory, immunomodulatory and anti-oxidant effects of Ocimum basilicum L. and its main constituents: A review. Iranian journal of basic medical sciences, 26(6), 617–627. https://doi.org/10.22038/IJBMS.2023.67466.14783

Xylia, P., Chrysargyris, A., Zengin, G., & Tzortzakis, N. (2025). The Contribution of Basil Essential Oil and Ascorbic Acid Application to the Preservation of Fresh Basil During Shelf Life. Journal of food science, 90(8), e70467. https://doi.org/10.1111/1750-3841.70467

Ayuob, N. N., Balgoon, M. J., Ali, S., Alnoury, I. S., ALmohaimeed, H. M., & AbdElfattah, A. A. (2020). Ocimum basilicum (Basil) Modulates Apoptosis and Neurogenesis in Olfactory Pulp of Mice Exposed to Chronic Unpredictable Mild Stress. Frontiers in psychiatry, 11, 569711. https://doi.org/10.3389/fpsyt.2020.569711

Vasincu, A., Rusu, R. N., Ababei, D. C., Bulea, D., Arcan, O. D., Vasincu, I. M., Beșchea Chiriac, S., Popescu, I. R., Bild, W., & Bild, V. (2025). The Neuroprotective Potential of Ocimum Plant Species: Seasoning the Mind with Sweet and Holy Basil. Nutrients, 17(17), 2877. https://doi.org/10.3390/nu17172877

—-

Ashokkumar, K., Simal-Gandara, J., Murugan, M., Dhanya, M. K., & Pandian, A. (2022). Nutmeg (Myristica fragrans Houtt.) essential oil: A review on its composition, biological, and pharmacological activities. Phytotherapy research : PTR, 36(7), 2839–2851. https://doi.org/10.1002/ptr.7491

Zhang, W. K., Tao, S. S., Li, T. T., Li, Y. S., Li, X. J., Tang, H. B., Cong, R. H., Ma, F. L., & Wan, C. J. (2016). Nutmeg oil alleviates chronic inflammatory pain through inhibition of COX-2 expression and substance P release in vivo. Food & nutrition research, 60, 30849. https://doi.org/10.3402/fnr.v60.30849

Rajeshwari Ullagaddi * Sri Sathya Sai University for Human Excellence, Department of Life Sciences, Karnataka, India. The aromatic cure: A scientific review of Nutmeg’s medicinal properties. International Journal of Science and Research Archive, 2025, 15(01), 1656-1663 Publication history: 28 April 2025 Article DOI: https://doi.org/10.30574/ijsra.2025.15.1.1197

Tariq, D., Sultan, M. T., Noman, A. M., Raza, H., Akram, S., Mohamed, H. M., Khan, M. A., Imran, M., Hussain, M., Memon, A. G., Atif, M., Mohamed, G. A., Ibrahim, S. R. M., & Jbawi, E. A. (2025). Nutmeg Beyond Spice: A Review on Its Therapeutic Potential, Safety and Industrial Promise. Food science & nutrition, 13(10), e71053. https://doi.org/10.1002/fsn3.71053

—-

Bina, F., & Rahimi, R. (2017). Sweet Marjoram: A Review of Ethnopharmacology, Phytochemistry, and Biological Activities. Journal of evidence-based complementary & alternative medicine, 22(1), 175–185. https://doi.org/10.1177/2156587216650793

Lee, S. W., Shin, Y. K., Lee, J. M., & Seol, G. H. (2023). Inhalation of Origanum majorana L. essential oil while working reduces perceived stress and anxiety levels of nurses in a COVID-19 intensive care unit: a randomized controlled trial. Frontiers in psychiatry, 14, 1287282. https://doi.org/10.3389/fpsyt.2023.1287282

Sarfaraz, D., Rahimmalek, M., Sabzalian, M. R., Gharibi, S., Matkowski, A., & Szumny, A. (2023). Essential Oil Composition and Antioxidant Activity of Oregano and Marjoram as Affected by Different Light-Emitting Diodes. Molecules, 28(9), 3714. https://doi.org/10.3390/molecules28093714

Ivanova, S., Dzhakova, Z., Gvozdeva, Y., Petkova, G., Ivanova, A., & Dzhambazova, E. (2025). The Role of Essential Oils in Sports Recovery and Performance. Molecules (Basel, Switzerland), 30(18), 3771. https://doi.org/10.3390/molecules30183771

—-

Meamarbashi A. (2014). Instant effects of peppermint essential oil on the physiological parameters and exercise performance. Avicenna journal of phytomedicine, 4(1), 72–78.

Meamarbashi, A., & Rajabi, A. (2013). The effects of peppermint on exercise performance. Journal of the International Society of Sports Nutrition, 10(1), 15. https://doi.org/10.1186/1550-2783-10-15

Ozmen, Tarik & Doğan, Hanife & Gunes Gencer, Gokce Yagmur. (2020). EFFECT OF CLASSIC MASSAGE WITH PEPPERMINT OIL ON MUSCLE SORENESS AND MUSCLE STRENGTH DURING RECOVERY FROM EXERCISE. 11. 103-111.

Chumpitazi, B. P., Kearns, G. L., & Shulman, R. J. (2018). Review article: the physiological effects and safety of peppermint oil and its efficacy in irritable bowel syndrome and other functional disorders. Alimentary pharmacology & therapeutics, 47(6), 738–752. https://doi.org/10.1111/apt.14519

—

Deng, W., Liu, K., Cao, S., Sun, J., Zhong, B., & Chun, J. (2020). Chemical Composition, Antimicrobial, Antioxidant, and Antiproliferative Properties of Grapefruit Essential Oil Prepared by Molecular Distillation. Molecules (Basel, Switzerland), 25(1), 217. https://doi.org/10.3390/molecules25010217

Miya, G., Nyalambisa, M., Oyedeji, O., Gondwe, M., & Oyedeji, A. (2021). Chemical Profiling, Toxicity and Anti-Inflammatory Activities of Essential Oils from Three Grapefruit Cultivars from KwaZulu-Natal in South Africa. Molecules (Basel, Switzerland), 26(11), 3387. https://doi.org/10.3390/molecules26113387

Zhang X, Xu H, Hua J, Zhu Z, Wang M. Protective Effects of Grapefruit Essential Oil against Staphylococcus Aureus-Induced Inflammation and Cell Damage in Human Epidermal Keratinocytes. Chem Biodivers. 2022 Jun;19(6):e202200205. doi: 10.1002/cbdv.202200205. Epub 2022 May 13. PMID: 35505451.

Bakó, E., Fehérvári, P., Garami, A., Dembrovszky, F., Gunther, E. E., Hegyi, P., Csupor, D., & Böszörményi, A. (2023). Efficacy of Topical Essential Oils in Musculoskeletal Disorders: Systematic Review and Meta-Analysis of Randomized Controlled Trials. Pharmaceuticals (Basel, Switzerland), 16(2), 144. https://doi.org/10.3390/ph16020144

—

Ikei, H., Song, C., & Miyazaki, Y. (2015). Physiological effect of olfactory stimulation by Hinoki cypress (Chamaecyparis obtusa) leaf oil. Journal of physiological anthropology, 34, 44. https://doi.org/10.1186/s40101-015-0082-2

Aoyagi, Y., Furuya, R., Kawasaki, M., Takenouchi, M., Ohashi, M., & Li, Q. (2026). Inhaled hinoki cypress essential oil improves saliva secretion and swallowing function in older adults with dysphagia: a randomized crossover study. Environmental health and preventive medicine, 31, 4. https://doi.org/10.1265/ehpm.25-00319

Chen CJ, Kumar KJ, Chen YT, Tsao NW, Chien SC, Chang ST, Chu FH, Wang SY. Effect of Hinoki and Meniki Essential Oils on Human Autonomic Nervous System Activity and Mood States. Nat Prod Commun. 2015 Jul;10(7):1305-8. PMID: 26411036.

—-

Sowndhararajan, K., & Kim, S. (2016). Influence of Fragrances on Human Psychophysiological Activity: With Special Reference to Human Electroencephalographic Response. Scientia pharmaceutica, 84(4), 724–751. https://doi.org/10.3390/scipharm84040724

___

Fatima, S., Farzeen, I., Ashraf, A., Aslam, B., Ijaz, M. U., Hayat, S., Sarfraz, M. H., Zafar, S., Zafar, N., Unuofin, J. O., Lebelo, S. L., & Muzammil, S. (2023). A Comprehensive Review on Pharmacological Activities of Pachypodol: A Bioactive Compound of an Aromatic Medicinal Plant Pogostemon Cablin Benth. Molecules (Basel, Switzerland), 28(8), 3469. https://doi.org/10.3390/molecules28083469

Mrisho, I. I., Musazade, E., Chen, H., Zhao, H., Xing, J., Li, X., Han, J., & Cai, E. (2025). Unlocking the Therapeutic Potential of Patchouli Leaves: A Comprehensive Review of Phytochemical and Pharmacological Insights. Plants (Basel, Switzerland), 14(7), 1034. https://doi.org/10.3390/plants14071034

Reichling J, Schnitzler P, Suschke U, et al. Essential oils of aromatic plants with antibacterial, antifungal, antiviral, and cytotoxic properties–an overview. J Complement Med Res. 2009; 16(2): 79-90.

Research

All of our products are blended, quality checked, packaged in glass and shipped directly from Wisconsin, USA.

SYMMETRY LLC